Pathogenesis of acanthamoebic keratitis: hypothesis based on a histological analysis of 30 cases.
نویسنده
چکیده
The results of a histopathological study of 30 cases of Acanthamoeba keratitis are construed as indicating a four stage pathogenetic sequence: (1) initial infection, involving breaching of the surface epithelium; (2) keratocyte depletion by the invading trophozoites; (3) inflammatory response mediated by neutrophil polymorphonuclear leucocytes; (4) stromal necrosis attributable to leucocytic activity.
منابع مشابه
Gamer Histopathological and related findings in individual patients with acanthamoebic Anterior stroma Posterior stroma Inflammation Inflammation Epithelial Cell Stromal Cell Stromal
The results of a histopathological study of 30 cases ofAcanthamoeba keratitis are construed as indicating a four stage pathogenetic sequence: (1) initial infection, involving breaching ofthe surface epithelium; (2) keratocyte depletion by the invading trophozoites; (3) inflammatory response mediated by neutrophil polymorphonuclear leucocytes; (4) stromal necrosis attributable to leucocytic acti...
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ورودعنوان ژورنال:
- The British journal of ophthalmology
دوره 77 6 شماره
صفحات -
تاریخ انتشار 1993